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Drug Interactions with Sildenafil Citrate

Sildenafil > sildenafil citrate drug


  • 7. Interactions
  • Dosing & Uses
  • Why is this medication prescribed?
  • Related/similar drugs

The following nonprescription or herbal products may interact with sildenafil: cimetidine (Tagamet HB), St.

Property Description Value Units
Molecular Weight The mass of one mole of sildenafil citrate 474.58 g/mol
Chemical Formula Molecular composition C22H30N6O4S
Solubility Water solubility Slightly soluble at 25°C
pH of Solution Typical pH when dissolved in water 3.8 - 4.2
Melting Point The temperature at which it melts 196 - 198 °C

John's wort.

  • Sildenafil citrate was first approved by the FDA in 1998.
  • Its brand name is Viagra, but generic versions are available.
  • The drug is available in tablets of various strengths, typically 25-100 mg.
  • It can be prescribed for both men and in specific cases, women.
  • Proper dosage varies based on health status and response.
  • Use caution in patients with heart problems or low blood pressure.
  • It is not a hormone or a testosterone booster.

Be sure to let your doctor and pharmacist know that you are taking these medications before you start taking sildenafil.

7. Interactions

Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily. If you are taking sildenafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire.

Report Problems to the Food and Drug Administration

Sildenafil does not prevent pregnancy or 50 mg sildenafil price the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). Sildenafil comes as a tablet and suspension (liquid) to take by mouth. If you are taking sildenafil to treat erectile dysfunction, follow your doctor's directions and the guidelines in this paragraph. Take sildenafil as needed before sexual activity. The best time to take sildenafil is about 1 hour before sexual activity, but you can take the medication any time from 4 hours to 30 minutes before sexual activity.

Viagra and herbs and supplements

Sildenafil usually should not be taken more than once every 24 hours. If you have certain health conditions or are taking certain medications, your doctor may tell you to take sildenafil less often. You can take sildenafil with or without food. However, if you take sildenafil with a high-fat meal, it will take longer for the medication to start to work. If you are taking sildenafil to treat PAH, you will probably take sildenafil three times a day with or without food. Do not start these medications while taking sildenafil without discussing it with your healthcare provider.

Product Dosage Quantity + Bonus Price
Viagra Generic50mg120 + 6 Pills129.64€ 123.47€
Kamagra100mg20 Pills86.09€ 81.99€
Kamagra Oral Jelly100mg30 + 5 Sachets136.20€ 129.71€
Kamagra Oral Jelly100mg63 + 7 Sachets224.18€ 213.50€
Viagra Generic100mg20 Pills45.58€ 43.41€
Viagra Generic150mg180 + 10 Pills236.46€ 225.20€
Viagra Generic100mg10 Pills28.91€ 27.53€
Viagra Generic150mg270 + 10 Pills326.61€ 311.06€
Viagra Generic200mg360 + 10 Pills481.98€ 459.03€
Viagra Generic150mg30 + 2 Pills72.32€ 68.88€

tell your doctor if you smoke, if you have had heart surgery within the last 6 months, if you have ever had an erection that lasted for more than 4 hours, and if you have recently lost a large amount of body fluids (dehydration).

Brand Name Manufacturer Formulation Type Typical Dosage Notes
Viagra Pfizer Tablet 25, 50, 100 mg Most well-known brand
Revatio Pfizer Tablet 20 mg For pulmonary hypertension
Sildenafil Citrate Various generic manufacturers Tablet 25, 50, 100 mg Generic versions available
Kamagra Ajanta Pharma Oral Gel 100 mg Used off-label in some countries

This can happen if you are sick with fever, diarrhea, or vomiting; sweat a lot; or do not drink enough liquids.

  • Sildenafil is available in most countries through prescription only.
  • It is used worldwide, with varying approval statuses.
  • FDA and EMA have rigorous testing standards for sildenafil.
  • Using the drug responsibly can lead to successful treatment outcomes.
  • Combining sildenafil with other medications requires medical supervision.
  • Be aware of the potential for drug interactions with heart or blood pressure meds.
  • Always consult a healthcare professional for personalized advice.

Also tell your doctor if you have or have ever had pulmonary veno-occlusive disease (PVOD; blockage of veins in the lungs); a stomach ulcer; heart, kidney, or liver disease; a heart attack; heart failure; angina (chest pain); an irregular heartbeat; a stroke; chest pain; high or low blood pressure; high cholesterol; a bleeding disorder; blood circulation problems; blood cell problems such as sickle cell anemia (a disease of the red blood cells), multiple myeloma (cancer of the plasma cells), or leukemia (cancer of the white blood cells); conditions affecting the shape of the penis (e.g., angulation, cavernosal fibrosis, or Peyronie's disease); or diabetes.

Dosing & Uses

Ask your pharmacist for a list of the ingredients. Some medications should not be taken with sildenafil. Make sure you have discussed any other medications you are currently taking or plan to take before starting sildenafil with your doctor and pharmacist. Before starting, stopping, or changing any medications while taking sildenafil, please get the advice of your doctor or pharmacist. tell your doctor if you are taking street drugs containing nitrates ('poppers') such as amyl nitrate, amyl nitrite, or butyl nitrate while taking sildenafil.

Drugs Affecting Gastric Acidity

Your 200mg sildenafil citrate doctor will tell you not to take sildenafil if you are taking street drugs containing nitrates. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. you should know that sildenafil is available under the brand names Liqrev, Revatio, and Viagra. You should only be treated with one of these products at a time. Also tell your doctor if you or any of your family members have or have ever had an eye disease such as retinitis pigmentosa (an inherited eye condition that causes loss of vision) or if you have ever had sudden severe vision loss, especially if you were told that the vision loss was caused by a blockage of blood flow to the nerves that help you see.

  • Contraindications include use with nitrates and recent heart attack.
  • Patients with contraindications should avoid sildenafil entirely.
  • Visual disturbances including blue-tinted vision may occur.
  • Use caution in patients with liver or kidney impairment.
  • Sildenafil can interact with certain antibiotics and antifungals.
  • Always inform your doctor about other medications you're taking.
  • It does not protect against sexually transmitted infections.

if you are a woman and you are taking sildenafil to treat PAH, tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking sildenafil, call your doctor.

Why is this medication prescribed?

Contact your doctor if you have additional questions about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Keep out of the reach of children Store at controlled room temperature, between 20°C to 25°C (68°F to 77°F) Throw away any unused medicine after the expiration date As with almost all medicine, the recommended treatments do not work for every single person. There is a risk the medicine will not work and your ED continues. If after more than 4 weeks your symptoms have not improved, you should consider scheduling an in-person visit with a doctor.

Incidence not known

Before you take sildenafil tablets, tell your healthcare provider if you: have or have had heart problems such as a heart attack, irregular heartbeat, angina, chest pain, narrowing of the aortic valve or heart failure have had heart surgery within the last 6 months have low blood pressure, or high blood pressure that is not controlled have had an erection that lasted for more than 4 hours have problems with your blood cells such as sickle cell anemia, multiple myeloma, or leukemia have retinitis pigmentosa, a rare genetic (runs in families) eye disease have ever had severe vision loss, including an eye problem called non-arteritic anterior ischemic optic neuropathy (NAION) have kidney problems or are having kidney dialysis Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take any of the following: medicines called guanylate cyclase stimulators, such as riociguat (Adempas) medicines called alpha blockers such as Hytrin® (terazosin HCl), Flomax® (tamsulosin HCl), Cardura® (doxazosin mesylate), Minipress® (prazosin HCl), Uroxatral® (alfuzosin HCl), Jalyn® (dutasteride and tamsulosin HCl), or Rapaflo® (silodosin). In some patients, the use of sildenafil tablets with alpha-blockers can lead to a drop in blood pressure or to fainting. medicines called HIV protease inhibitors, such as ritonavir (Norvir®), indinavir sulfate (Crixivan®), saquinavir (Fortovase® or Invirase®) or atazanavir sulfate (Reyataz®) some types of oral antifungal medicines, such as ketoconazole (Nizoral®), and itraconazole (Sporanox®) some types of antibiotics, such as clarithromycin (Biaxin®), telithromycin (Ketek®), or erythromycin other medicines that treat high blood pressure Sildenafil tablets contain sildenafil, which is the same medicine found in another drug called REVATIO®. REVATIO® is used to treat a rare disease called pulmonary arterial hypertension (PAH).

What to do if you think you’ve taken too much Viagra

Sildenafil tablets should not be used with REVATIO® or with other PAH treatments containing sildenafil or any other PDE5 inhibitors (such as Adcirca® (tadalafil)). Telemedicine does not replace your primary care physician. It is important to keep your primary care physician and pharmacist informed of all medications you are taking, including those in your Keeps treatment plan, as they can interact with other medicines you may be taking. Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Liqrev, Revatio) is used to improve the ability to exercise in adults (Liqrev, Revatio) and children 1 year of age and older (Revatio) with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking sildenafil. if you are taking sildenafil to treat erectile dysfunction, tell your doctor if you have ever been advised by a healthcare professional to avoid sexual activity for medical reasons or if you have ever experienced chest pain during sexual activity.

  • Sildenafil citrate is a medication used primarily for erectile dysfunction.
  • It works by relaxing blood vessels to increase blood flow.
  • Sildenafil is also prescribed for pulmonary arterial hypertension.
  • Common side effects include headache, flushing, and nasal congestion.
  • It should be taken 30-60 minutes before sexual activity.
  • Alcohol and high-fat meals can reduce its effectiveness.
  • Do not take with nitrate medications due to risk of severe hypotension.

Sexual activity may be a strain on your heart, especially if you have heart disease.

Related/similar drugs

Take sildenafil at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor. Shake the liquid well for 10 seconds before each use to mix the medication evenly. Use the oral syringe provided with your medication to measure and take your dose.

Drug Interactions

Follow the manufacturer's directions to use and clean the oral syringe. Do not mix the liquid with other medications or add anything to flavor the medication. If you are taking sildenafil for erectile dysfunction, your doctor will probably start you on an average dose of sildenafil and increase or decrease your dose depending on your response to the medication. Tell your doctor if sildenafil liquid sildenafil citrate is not working well or if you are experiencing side effects. If you are taking sildenafil for PAH, you should know that sildenafil controls PAH but does not cure it.

Mild side effects

Continue to take sildenafil even if you feel well. Do not stop taking sildenafil without talking to your doctor. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. tell your doctor and pharmacist if you are allergic to sildenafil, any other medications, or any of the ingredients in sildenafil tablet or suspension. If you experience chest pain, dizziness, or nausea during sexual activity, call your doctor immediately and avoid sexual activity until your doctor tells you otherwise.

Storage Condition Details Temperature Range Light Exposure Humidity
Preferred Storage Cool, dry place 15-30°C Keep in original container Avoid humidity
Keep away from light Protect from direct sunlight N/A Yes N/A
Out of reach of children Safety precaution N/A N/A N/A
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